Elevated levels of IL-8 in fatal leptospirosis
نویسندگان
چکیده
منابع مشابه
Elevated Serum Levels of IL-6 and TNF-α in Patients with Irritable Bowel Syndrome
Introduction: Irritable bowel syndrome (IBS) is accompanied by abdominal pain and intestinal discomforts. A line of evidence shows that the immune system plays important roles in the pathogenesis of the disease. Two main cytokines directing the immune system are IL-6 and TNF-α which may play a role in the immunopathogenesis of this disease. The present study aimed at investigating the serum lev...
متن کاملElevated serum IL-8 levels are associated with disease activity in idiopathic intermediate uveitis.
AIM To find a laboratory indicator for systemic involvement in intermediate uveitis. METHODS Interleukin 8 (IL-8) and C reactive protein (CRP) serum levels were measured in patients with idiopathic intermediate uveitis (n = 61), uveitis controls (n = 143), and normal controls (n = 29). The records of those with intermediate uveitis were reviewed with the emphasis on disease activity and sever...
متن کاملCathelicidin Insufficiency in Patients with Fatal Leptospirosis
Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10-50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms associated with case fatality. Whole blood transcriptional profiling of 16 hospitalized Brazilian pa...
متن کاملElevated Serum Levels of IL-21 in Kawasaki Disease
PURPOSE The serum level of immunoglobulin (Ig)E has been reported to be elevated in patients with Kawasaki disease (KD). We investigated whether interleukin (IL)-21, rather than IL-4, could be related to elevated serum levels of IgE in KD. METHODS Sera from 48 patients with KD and 12 controls with high fever were collected to determine the level of IgE using an immunoassay system and the leve...
متن کاملFatal leptospirosis presenting as musculoskeletal chest pain.
After holidaying in Vanuatu, a 24-year-old man presented with pleuritic chest pain and chest wall tenderness thought to be musculoskeletal in origin. He developed fatal acute renal failure, jaundice, respiratory failure, myocarditis and rhabdomyolysis. Subsequent serological results showed a rise in serum titre of antibodies to Leptospira grippotyphosa, from 1 : 50 to 1 : 800, consistent with a...
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ژورنال
عنوان ژورنال: Pathogens and Global Health
سال: 2020
ISSN: 2047-7724,2047-7732
DOI: 10.1080/20477724.2020.1724356